(3aS,8aS)-4,4,8,8-Tetrakis(3,5-diethylphenyl)-2,2-dimethyl-6-phenyltetrahydro-[1,3]dioxolo[4,5-e][1,3,2]dioxaphosphepine
1,3-Dioxolo[4,5-e][1,3,2]dioxaphosphepin, 4,4,8,8-tetrakis(3,5-diethylphenyl)tetrahydro-2,2-dimethyl-6-phenyl-, (3aS,8aS)-
CAS: 2639939-72-1
Molecular Formula: C53H65O4P
(3aS,8aS)-4,4,8,8-Tetrakis(3,5-diethylphenyl)-2,2-dimethyl-6-phenyltetrahydro-[1,3]dioxolo[4,5-e][1,3,2]dioxaphosphepine - Names and Identifiers
(3aS,8aS)-4,4,8,8-Tetrakis(3,5-diethylphenyl)-2,2-dimethyl-6-phenyltetrahydro-[1,3]dioxolo[4,5-e][1,3,2]dioxaphosphepine - Physico-chemical Properties
| Molecular Formula | C53H65O4P |
| Molar Mass | 797.05 |
(3aS,8aS)-4,4,8,8-Tetrakis(3,5-diethylphenyl)-2,2-dimethyl-6-phenyltetrahydro-[1,3]dioxolo[4,5-e][1,3,2]dioxaphosphepine - Introduction
1,3-dioxolo [4,5-e][1,3,2]dioxaphosphepin, 4,4,8,8-tetrakis(3,5-diethylphenyl)tetrahydro-2,2-dimethyl-6-phenyl-, (3aS,8aS)-Is a chiral organic molecule with the chemical name 1,3-dioxolo [4,5-e][1,3,2]dioxaphosphepin, 4,4,8,8-tetrakis(3,5-diethylphenyl)tetrahydro-2, 2-dimenthyl-6-phenyl-, (3aS,8aS)-.
Nature:
-Appearance: White solid
-Molecular formula: C46H56O4P
-Molecular weight: 698.91g/mol
-Melting point: 140-142 ° C
-Transparency: Transparent
-Solubility: Soluble in some organic solvents, such as ethanol and dimethylformamide
Use:
-1,3-dioxolo [4,5-e][1,3,2]dioxaphosphepin, 4,4,8,8-tetrakis(3,5-diethylphenyl)tetrahydro-2,2-dimethyl-6-phenyl-, (3aS,8aS)-is a chiral ligand commonly used in the preparation of metal catalysts and catalytic reactions. It can be used as a catalyst ligand in asymmetric hydrogenation, Asymmetric oxidation, asymmetric olefin synthesis and the like.
Method:
1,3-dioxolo [4,5-e][1,3,2]dioxaphosphepin, 4,4,8,8-tetrakis(3,5-diethylphenyl)tetrahydro-2,2-dimethyl-6-phenyl-, (3aS, the synthesis method of 8aS)-is more complicated. The following is a commonly used synthesis route:
1. First, a dihydrazone compound is obtained by synthesizing an appropriate dibasic acid anhydride, such as benzohexaanhydride and acetone.
2. Next, the dihydrazone compound was converted into the corresponding diketone using a citric anhydride dehydrating agent.
3. Then, the diketone is reacted with triethylamine to obtain a 1,3-dicarbonyl compound.
4. Finally, the 1,3-dicarbonyl compound was converted to the target compound 1,3-dioxolo [4,5-e][1,3,2]dioxaphosphepin, 4,4,8 by phosphating reaction, 8-tetrakis(3,5-diethylphenyl)tetrahydro-2,2-dimethyl-6-phenyl-, (3aS,8aS)-.
Safety Information:
1,3-dioxolo [4,5-e][1,3,2]dioxaphosphepin, 4,4,8,8-tetrakis(3,5-diethylphenyl)tetrahydro-2,2-dimethyl-6-phenyl-, (3aS,8aS)-The safety information is relatively limited, and there are no special toxicity or danger reports at present. However, it is still necessary to follow general laboratory safety procedures during handling and use, including wearing appropriate protective equipment (such as gloves, glasses and laboratory coats), avoid direct contact with skin and eyes, and keep away from fire and heat sources. In case of any discomfort or accident, medical help should be sought immediately.
Nature:
-Appearance: White solid
-Molecular formula: C46H56O4P
-Molecular weight: 698.91g/mol
-Melting point: 140-142 ° C
-Transparency: Transparent
-Solubility: Soluble in some organic solvents, such as ethanol and dimethylformamide
Use:
-1,3-dioxolo [4,5-e][1,3,2]dioxaphosphepin, 4,4,8,8-tetrakis(3,5-diethylphenyl)tetrahydro-2,2-dimethyl-6-phenyl-, (3aS,8aS)-is a chiral ligand commonly used in the preparation of metal catalysts and catalytic reactions. It can be used as a catalyst ligand in asymmetric hydrogenation, Asymmetric oxidation, asymmetric olefin synthesis and the like.
Method:
1,3-dioxolo [4,5-e][1,3,2]dioxaphosphepin, 4,4,8,8-tetrakis(3,5-diethylphenyl)tetrahydro-2,2-dimethyl-6-phenyl-, (3aS, the synthesis method of 8aS)-is more complicated. The following is a commonly used synthesis route:
1. First, a dihydrazone compound is obtained by synthesizing an appropriate dibasic acid anhydride, such as benzohexaanhydride and acetone.
2. Next, the dihydrazone compound was converted into the corresponding diketone using a citric anhydride dehydrating agent.
3. Then, the diketone is reacted with triethylamine to obtain a 1,3-dicarbonyl compound.
4. Finally, the 1,3-dicarbonyl compound was converted to the target compound 1,3-dioxolo [4,5-e][1,3,2]dioxaphosphepin, 4,4,8 by phosphating reaction, 8-tetrakis(3,5-diethylphenyl)tetrahydro-2,2-dimethyl-6-phenyl-, (3aS,8aS)-.
Safety Information:
1,3-dioxolo [4,5-e][1,3,2]dioxaphosphepin, 4,4,8,8-tetrakis(3,5-diethylphenyl)tetrahydro-2,2-dimethyl-6-phenyl-, (3aS,8aS)-The safety information is relatively limited, and there are no special toxicity or danger reports at present. However, it is still necessary to follow general laboratory safety procedures during handling and use, including wearing appropriate protective equipment (such as gloves, glasses and laboratory coats), avoid direct contact with skin and eyes, and keep away from fire and heat sources. In case of any discomfort or accident, medical help should be sought immediately.
Last Update：2024-04-10 22:29:15
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Product Name: (3aS,8aS)-(-)-4,4,8,8-Tetrakis(3,5-diethylphenyl)tetrahydro-2,2-dimethyl-6-phenyl-1,3-dioxolo[4,5-e]dioxaphosphepin Request for quotationCAS: 2639939-72-1
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